BDBM10890 1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide::CHEMBL77517::Compound 6::E7070::Indisulam (IND)::Sulfonamide, 7

SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12

InChI Key InChIKey=SETFNECMODOHTO-UHFFFAOYSA-N

Data  184 KI  5 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10890   

TargetCarbonic anhydrase 14(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  104nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Medical University Of Gdansk

Curated by ChEMBL
LigandPNGBDBM10890(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Affinity DataKi:  104nMAssay Description:Inhibition of human full length carbonic anhydrase 14 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed